it does say it helps, not is directly causes such and such. When introduced after acetylcholine, atropine exhibited excitatory actions that increased the pacemaker frequency. For example, acetylcholine (ACh), an excitatory neurotransmitter, is broken down by acetylcholinesterase (AChE). Correspondence: J. Y. Liu ([email protected]). Example: acetylcholine (ACh) Binding of acetylcholine to its receptors on the postsynaptic cell opens up ligand-gated sodium channels. Neurotransmitters are chemical compounds that transfer information from nerve cells to body tissues. In the central nervous system, its role is primarily excitatory. Atropine, but not hexamethonium, reversed the inhibitory actions of acetylcholine. Acetylcholine works together with the neurotransmitter dopamine to enable smooth movements. The effect of acetylcholine (ACh) on pacemaking and spontaneous contractions in the gastrointestinal tract is not well characterized. explain. B. Acetylcholine is mainly seen as an excitatory type neurotransmitter, but it can also exert an inhibitory action depending on the type of synapse in which it acts. Alzheimer’s disease medication fact sheet. 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